Hi Tanyeem,
This is an individual trader decision. Here is what I normally do. If my EA has an open profitable trade I will normally keep it open over the weekend. This allows my EA to continue to profit from the current favorable market conditions. However, if my open trade is close to hitting the TP I will normally go ahead and close the trade. However, if my current EA is in a losing position I will normally close the trade on Friday. This will allow my EA to start a new position the following week.
Alan,